Mark Alvin Atkinson, Ph.D.
Sebastian Family Professor and Eminent Scholar
Department of Pathology, Immunology and Laboratory Medicine
College of Medicine
University of Florida

ORIGINAL PUBLICATIONS

  1. *Atkinson, M.A.; Maclaren, N.K.; Riley, W.J.; Winter, W.E.; Fisk, D.D.; Spillar, R.P.:  Are Insulin Autoantibodies, Markers for Insulin-Dependent Diabetes Mellitus?  Diabetes 35, 1986, pp. 894-898.
  2. *Beppu, H.; Winter, W.E.; Atkinson, M.A.; Maclaren, N.K.; Fujita, K.; Takahashi, H.: Bovine Albumin Antibodies in NOD Mice.  Diabetes Research 6, 1987, pp. 67-69.
  3. *Maclaren, N.; Riley, W.; Skordis, N.; Atkinson, M.; Spillar, R.; Silverstein, J.; Klein, R.; Rotter, J.: Inherited Susceptibility to Insulin Dependent Diabetes is Associated with HLA-DR 1, While DR5 is Protective. Autoimmunity 1, 1988, pp. 197-205.
  4. *Atkinson, M.A.; Maclaren, N.K.: Autoantibodies in Non-Obese Diabetic Mice Immunoprecipitate an M r 64,000 Islet Cell Antigen. Diabetes 37, 1988, pp. 1587-1590.
  5. *Atkinson, M.A.; Winter, W.E.; Skordis, N.K.; Beppu, H.; Riley, W.J.; Maclaren, N.K.: The Effect of Diet on the Prevalence and Onset of Insulin Dependent Diabetes in the BB Rat. Autoimmunity 2, 1988, pp. 11-20.
  6. *Riley, W.J.; Atkinson, M.A.; Schatz, D.A.; Maclaren, N.K.: Comparison of Islet Autoantibodies in "Pre-diabetes" and Recommendations for Screening. The Journal of Autoimmunity 3, 1990, pp. 47-52.
  7. *Atkinson, M.A.; Maclaren, N.K.; Holmes, L.A. ; Scharp, D.W.; Lacy, P.E.; Riley, W.J.: The Natural History and Predictive Value of M r 64,000 Autoantibodies for Insulin Dependent Diabetes. The Journal of Autoimmunity 3, 1990, pp. 41-46.
  8. *Atkinson, M.A.; Maclaren, N.K.; Riley, W.J.; Scharp, D.W.; Lacy, P.E.: M r 64,000 Autoantibodies as Predictors of Insulin Dependent Diabetes. The Lancet 335, 1990, pp. 1357-1360.
  9. Atkinson, M.A.; Maclaren, N.K.: What Causes Diabetes? Scientific American July 1990, pp. 62-67.
  10. *Atkinson, M.A.; N.K. Maclaren; Luchetta, R.; Burr, I. : Prophylactic insulin therapy prevents Insulitis and Insulin Dependent Diabetes in Non-Obese Diabetic Mice. Diabetes 39, 1990, pp. 933-937.
  11. *Atkinson, M.A.; Maclaren, N.K.; Scharp, D.W.: No Evidence for HSP 65 in Insulin Dependent Diabetes. The Lancet 336, 1990, pp. 1250-1251.
  12. *Atkinson, M.A.; Holmes, L.A. ; Sharp, D.W.; Lacy, P.E.; Maclaren, N.K.: No Evidence for Serological Autoimmunity Toward Islet Cell Heat Shock Proteins in Insulin Dependent Diabetes. The Journal of Clinical Investigation 87, 1991, pp. 721-724.
  13. *Kaufman, D.L.; Erlander, M.G.; Clare-Salzler, M.C.; Atkinson, M.A.; Maclaren, N.K.; Tobin, A.J.: Autoimmunity to two forms of Glutamate Decarboxylase in Insulin Dependent Diabetes. The Journal of Clinical Investigation 89, 1992, pp. 283-292.
  14. *Atkinson, M.A.; Kaufman, D.L.; Campbell, L.; Gibbs, K.A.; Shah, S.C.; Bu, D.F.; Erlander, M.G.; Tobin, A.J.; Maclaren, N.K.: Peripheral Blood Mononuclear Cells Respond to Glutamate Decarboxylase in Insulin Dependent Diabetes. The Lancet 339, 1992, pp. 548-549.
  15. Maclaren, N.K.; Atkinson, M.A.: Is Insulin Dependent Diabetes Environmentally Induced? The New England Journal of Medicine 327, 1992, pp.348-349.
  16. *Atkinson, M.A.; Kaufman, D.L.; Tobin, A.J.; Maclaren, N.K.: Islet Cell Autoantibodies Reactive to Glutamate Decarboxylase in Insulin Dependent Diabetes. The Journal of Clinical Investigation. 91, 1992, pp. 350-356.
  17. *Atkinson, M.A.; Maclaren, N.K.: Islet Cell Autoantigens. Diabetes Reviews 1: 1993, pp. 191-203.
  18. *Huang, L.; Atkinson, M.A.; Dush, P.; Kennedy, R.T.: Amperometric Monitoring of Individual Exocytosis Events in Pancreatic Beta Cells. Analytical Chemistry 65, 1993, pp. 1882-1887.
  19. *Atkinson, M.A.; Maclaren, N.K.: Islet Cell Autoantigens in Insulin Dependent Diabetes. The Journal of Clinical Investigation 92: 1993, pp. 1608-1616.
  20. *Kaufman, D.L.; Clare-Salzler, M.C.; Sercarz, E.E.; Tobin, A.J.; Atkinson, M.A.; Lehmann, P.: Spontaneous Loss of Self Tolerance to Glutamate Decarboxylase is a Key Event in the Pathogenesis of Murine Insulin-Dependent Diabetes. Nature 366: 1993, pp. 69-71.
  21. *Atkinson, M.A.; Bowman, M.A.; Kao, K.J.; Campbell, L.; Dush, P.J.; Simmel, O.; Maclaren, N.K.: Lack of Immune Responses to Bovine Serum Albumin in Insulin Dependent Diabetes. The New England Journal of Medicine 329, 1993, pp. 1853-1858.
  22. *Bowman, M.A.; Leiter, E.H.; Atkinson, M.A.: Prevention of Diabetes in the NOD Mouse: Implications for Therapeutic Intervention in Human Disease. Immunology Today 15, 1994, pp. 115-120.
  23. Atkinson, M.A.; Kao, K.J.; Maclaren, N.K.: Lack of Immunity to Bovine Serum Albumin in Insulin Dependent Diabetes. The New England Journal of Medicine 330, 1994, pp. 1616-1617.
  24. Leslie, R.D.G.; Atkinson, M.A.: Inverse Relation Between Humoral and Cellular Immunity to Glutamic Acid Decarboxylase in Insulin Dependent Diabetes. The Journal of Endocrinological Investigation 17, 1994, pp.581-584
  25. *Atkinson, M.A.; Bowman, M.A.; Campbell, L.; Kaufman, D.L.; Maclaren, N.K.: Cellular Immunity to a Determinant Common to Glutamate Decarboxylase and Coxsackie Virus in Insulin Dependent Diabetes. The Journal of Clinical Investigation 94, 1994, pp. 2125-2129.
  26. *Atkinson, M.A.; Maclaren, N.K.: The Pathogenesis of Insulin Dependent Diabetes. The New England Journal of Medicine 331, 1994, pp. 1428-1436.
  27. *Gerling, I. ; Atkinson, M.A.; Leiter, E.H.: The Thymus as a Site for Evaluating the Potency of Candidate b Cell Autoantigens in NOD mice. The Journal of Autoimmunity 7, 1994, pp. 851-858.
  28. *Schott, M.; Schatz, D.; Atkinson, M.; Krischer, J.; Mehta, H.; Vold, B.; Maclaren, N.: GAD 65 Autoantibodies Increase the Predictability but not the Sensitivity of Islet Cell and Insulin Autoantibodies for Developing Insulin Dependent Diabetes Mellitus. The Journal of Autoimmunity 7, 1994, pp. 865-872.
  29. Atkinson, M.A.; Ellis, T.M.: Should We Replace Islet Cell Antibody Assay For The Prediction of Insulin Dependent Diabetes. Diabetes Prevention & Therapy 8, 1994, pp. 33-34.
  30. *Hanson, M.S.; Serreze, D.V.; Atkinson, M.A. et al: Clonal Diversion of T Cell Responses from Th1 to Th2: A Possible Mechanism of Diabetes Resistance in NOD- Ea d Transgenic Mice. Autoimmunity 21, 1995, pp. 52-56.
  31. Atkinson, M.A.; Schatz, D.S.: Cow's Milk and IDDM: Only Time Will Tell. Diabetes Prevention & Therapy 9, 1995, pp. 1-2.
  32. *Huang, L.; Shen, H.; Atkinson, M.A.; Kennedy, R.T.: Detection of Exocytosis At Individual Pancreatic b cells by Amperometry at a Chemically Modified Microelectrode. Proceedings of The National Academy of Sciences , USA 92, 1995, pp. 9608-9612.
  33. *Daw, K.; Ujihara, N.; Atkinson, M.A.; Powers, A.C.: Glutamic Acid Decarboxylase Autoantibodies in Stiff-Man Syndrome and Insulin Dependent Diabetes Mellitus Exhibit Similarities and Differences in Epitope Recognition. The Journal of Immunology 156, 1996, pp. 818-825.
  34. *Ellis, T.M.; Atkinson, M.A.: The Clinical Significance of an Autoimmune Response against Glutamic Acid Decarboxylase. Nature Medicine 2, 1996, pp.148-153.
  35. *Bowman, M.A.; Campbell, L.; Darrow, B.; Suresh, A.; Clare-Salzler, M.; Atkinson, M.A.: Immunologic and Metabolic Effects of Prophylactic Insulin Therapy in Insulin Dependent Diabetes. Diabetes 45, 1996, pp. 205-208.
  36. *Tian, J.; Atkinson, M.A.; Clare-Salzler, M.; Herschenfeld, A.; Forsthuber, T.; Lehmann, P.V.; Kaufman, D.L.: Nasal Administration of Glutamate Decarboxylase (GAD 65) Peptides Induces Th2 Responses and Prevents Murine Insulin-Dependent Diabetes. The Journal of Experimental Medicine 183, 1996, pp. 1561-1567.
  37. *Ellis, T.M.; Atkinson, M.A.: Early Infant Diets and Insulin Dependent Diabetes. The Lancet 347, 1996, pp. 1464-1465.
  38. *Aanstoot, H.J.; Kim, J.; Knip, M.; Atkinson, M.A.; Mose-Larsen, P.; Fey, S.; Fu, Q.; Ludvigsson, J.; Landin, M.; Bruining, J.; Maclaren, N.K.; Akerblom, H.K.; Baekkeskov, S.: Identification and Characterization of a 38kD pancreatic B-cell antigen which along with glutamic acid decarboxylase marks the early phases of autoimmune response in type 1 diabetes. The Journal of Clinical Investigation 97, 1996, pp. 2772-2783.
  39. *Hanson, M.S.; Cetkovic-Cvrlje, M.; Ramiya, V.K.; Atkinson, M.A.; Maclaren, N.K.; Singh, B.; Elliott, J.F.; Serreze, D.V.; Leiter, E.K.: Quantitative Thresholds of MHC Class II I-E Expressed on Hematopoietically Derived APC in Transgenic NOD/Lt Mice Determine Levels of Diabetes Resistance and Indicate Mechanism of Protection. The Journal of Immunology 157, 1996, pp. 1279-1287.
  40. *Bowman, M.A.; Simell, O.G.; Peck, A.B.; Cornelius, J.; Luchetta, R.; Look, Z.; Maclaren, N.K.; Atkinson, M.A.: Pharmacokinetics of Aminoguanidine Administration and Effects on the Diabetes Frequency in Nonobese Diabetic Mice. The Journal of Pharmacology and Experimental Therapeutics 279, 1996, pp. 790-794.
  41. *Maclaren, N.K.; Atkinson, M.A.: Insulin-Dependent Diabetes Mellitus: the Hypothesis of Molecular Mimicry Between Islet Cell Antigens and Microorganisms. Molecular Medicine 3, 1997, pp. 76-83.
  42. *Atkinson, M.A.: Diet, Genetics, and Diabetes: The Role of Infant Nutrition in the Pathogenesis of Insulin Dependent Diabetes. Food Technology 51, 1997, pp. 77-79.
  43. *Cetkovic-Cvrlje, M.; Gerling, I.C.; Muir, A.; Atkinson, M.A.; Elliot, J.F.; Leiter, E.H.: Amelioration or Acceleration of Diabetes in NOD/Lt Mice Mediated by Intrathymic Administration of Candidate Beta Cell Autoantigens. Diabetes 46, 1997, pp. 1975-1983.
  44. *Tian, J.; Clare-Salzler, M.C.; Herschenfeld, A.; Middleton, B.; Newman, D.; Evans, C.; Atkinson, M.A.; Mueller, R.; Mullen, Y.; Sarvetnick, N.; Tobin, A.J.; Kaufman, D.L.: Glutamate Decarboxylase Administration Inhibits Disease Progression in Prediabetic Mice and Prolongs Survival of Transplanted Islets in Diabetic Mice. Nature Medicine 2, 1996, pp. 1348-1353.
  45. *Atkinson, M.A.; Gendreau, P.; Rinker, C.; Ellis, T.; Petitto, J.: NOD Mice as a Model for Inherited Deafness. Diabetologia 56, 1997, pp. 501-502.
  46. *Atkinson, M.A.; Ellis, T.M.: Infant Diets and Insulin Dependent Diabetes: Evaluating the “Cows Milk Hypothesis” and a Role for anti-Bovine Serum Albumin Immunity. Journal of the American College of Nutrition 16 , 1997, pp. 334-340.
  47. *Atkinson, M.A.: Molecular Mimicry and the Pathogenesis of Insulin Dependent Diabetes Mellitus: Still Just an Attractive Hypothesis. Annals of Medicine 29, 997, pp. 76-84.
  48. *Ellis, T.M.; Hardt , N.S. ; Atkinson, M.A.: Cellular Immune Activities in Women with Silicone Breast Implants. Annals of Allergy, Asthma, & Immunology 79, 1997, pp. 151-154.
  49. Atkinson, M.A.: Mechanisms Underlying the Loss of Self-Tolerance in NOD Mice. Research in Immunology 148, 1997, pp. 301-307.
  50. *Wilson, S.B.; Kent, S.C.; Patton, K.T.; Orban, T.; Jackson, R.A.; Exley, M.; Porcelli, S.; Schatz, D.A.; Atkinson, M.A.; Balk, S.P.; Strominger, J.L.; Hafler, D.A.: Extreme Th1 Bias of Invariant V a 24J a Q T cells in Type 1 Diabetes. Nature 391, 1998, pp.1348-1353.
  51. *Zechel, M.A.; Elliott, J.F.; Atkinson, M.A.; Singh, B.: Characterization of Novel T-cell Epitopes on 65 kDa and 67 kDa Glutamic Acid Decarboxylase Relevant in Autoimmune Responses in NOD Mice The Journal of Autoimmunity 11, 1998, pp. 83-95.
  52. *Ellis, T.; Schatz, D.; Ottendorffer, E.: Wasserfall, C.; Lan, M.; Notkins, A.; Maclaren, N.; Atkinson, M.: Relationship between humoral and Cellular Immunity to IA-2 in Insulin Dependent Diabetes. Diabetes 47, 1998, pp. 566-569.
  53. *Ellis, T.; Jodoin, E.; Schatz, D.; Ottendorffer, E.: She, J.S.; Atkinson, M.: Cellular Immune Responses Against b Casein: Elevated but not Specific for Persons with Insulin Dependent Diabetes. Diabetologia 41, 1998, pp. 731-735.
  54. *Schatz, D.; Ellis, T.; Ottendorfer, E.; Jodoin, E.; Salisbury, P.; Barrett, D.; Atkinson, M.: Aging and the Immune Response to Tetanus Toxoid: Diminished Frequency and Level of Cellular Immune Reactivity to Antigenic Stimulation. Clinical Diagnostic Lab oratory Immunology 5, 1998, pp. 894-896.
  55. * Song, S.; Morgan, M.; Ellis, T.; Poirer, A.; Chesnut, K.; Wang, J.; Brantly, M.; Byrne, B.J.; Atkinson, M.; Flotte, T.R.: Sustained Secretion of Human Alpha-1-Antitrypsin from Murine Muscle Transduced with Adeno-Associated Virus Vector. Proceedings of The National Academy of Sciences , USA 95, 1998, pp. 14384-14388.
  56. *Leslie, D.; Atkinson, M.A.; Notkins, A. L.: Autoantigens IA-2 and GAD in Type 1 (Insulin Dependent) Diabetes. Diabetologia 42, 1999, pp. 3-14.
  57. *Ellis, T.: Jodoin, E.; Ottendorffer, E.; Salisbury , P.; She, J.X.; Schatz, D.; Atkinson, M.A.: Cellular Immune Activities against proinsulin: No Evidence for Enhanced Reactivity in Individuals with Insulin Dependent Diabetes Mellitus. Diabetes 48, 1999, pp. 299-303.
  58. Wilson, S.B.; Kent, S.C.; Patton, K.T.; Orban, T.; Jackson, R.A.; Exley, M.; Porcelli, S.; Schatz, D.A.; Atkinson, M.A.; Balk, S.P.; Strominger, J.L.; Hafler, D.A.: Extreme Th1 Bias of Invariant V a 24J a Q T cells in Type 1 Diabetes. Nature 399, 1999, pp. 84.
  59. *Falta, M.T.; Magin, G.K.; Allegretta, M.; Steinman, L.; Atkinson, M.A.; Brostoff, S.W.; Albertini, R.: Selection of hprt Mutant T Cells as Surrogates for Dividing Cells Reveals a Restricted T Cell Receptor BV Repertoire in Insulin-Dependent Diabetes Mellitus. Clinical Immunology 90, pp. 340-351, 1999.
  60. *Atkinson, M.A.; Leiter, E.H.: The NOD Mouse Model of Type 1 Diabetes Mellitus: As Good As It Gets? Nature Medicine 5, pp. 601-604, 1999.
  61. *She, J.S.; Ellis, T.; Wilson, B.; Wasserfal, E.; Kent, S.; Hafler, D.; Schatz, D.; Muir, A.M.; Strominger, J.; Atkinson, M.: Heterophile Antibodies Segregate in Families and are Associated with Protection from Type 1 Diabetes. Proceedings of The National Academy of Sciences, USA 96, pp. 8116-8119, 1999.
  62. *Ottendorfer, E.; Ellis, T.M.; Bahjat, K.S.; Clare-Salzler, M.; Atkinson. M.A.: No Alteration in T Lymphocyte Expression of CD40 Ligand (CD154) in Individuals with or at Increased Risk for Insulin-Dependent Diabetes Mellitus. The Journal of Clinical Endocrinology and Metabolism 84, pp. 4068-4072, 1999.
  63. *Roep, B.O., Atkinson, M.A.; van Endert, P.M.; Gottlieb, P.A.; Wilson, .B.; Sachs, J.A.; for the workshop participants: Autoreactive T-cell Responses in Insulin-Dependent (Type 1) Diabetes Mellitus: Report of the First International Workshop for Standardization of T-cell Assays. The Journal of Autoimmunity 13, pp. 267-282, 1999.
  64. Atkinson, M.A.; Ellis, T.M.; Serreze, D.V.: Control of Autoimmune Diabetes in NOD Mice by GAD Expression or Suppression in b Cells. Science 287, pp. 191-192, 2000.
  65. *Wasserfall, C.; Atkinson, M.; Jodoin, E.; Schatz, D.; She, J.X.; Ellis, T.M.: Glutamic Acid Decarboxylase and IA-2 Autoantibodies in Type 1 Diabetes; Comparing Sample Substrates for Autoantibody Determination. Pediatric Diabetes 1: 10-16, 2000.
  66. *Serreze, D.; Ottendorfer, E.; Gauntt, C.; Ellis, T.M.; Atkinson, M.A.: Acceleration of Insulin Dependent Diabetes Mellitus by a Coxsackievirus Infection Requires a Preexisting Critical Mass of Autoreactive T cells in Pancreatic Islets. Diabetes 49: 708-711, 2000.
  67. *Atkinson, M.; Honeyman, M.; Peakman, M.; Roep, B.: Standardization of T Cell Assays in Type 1 Diabetes Diabetologia 43: 819-20, 2000.
  68. *Falta, M. T.; Atkinson, M.; Allegretta, M.; Vacek, P.M.; Albertini, R.J.: Azathioprine Associated T-Cell Mutations in Insulin-Dependent Diabetes Mellitus. Scandinavian Journal of Immunology 51: 626-634, 2000.
  69. Atkinson, M.: The $64,000 Question in Diabetes Continues. The Lancet 356: 4-6, 2000.
  70. Haskins, K.: Atkinson, M.: Predicting Disease in Animal Models of Type 1 Diabetes: Lessons for Studies of Humans? The Journal of Autoimmunity 16: 15-19, 2001.
  71. *Flotte, T.; Song, S.; Wang, J.; Chesnut, K.; Wasserfall, C.; Kapturczak, M.; Ellis, T.; Agarwal, A.; Nick, H,; Atkinson.: Efficient Ex Vivo Transduction of Pancreatic Islet Cells with Recombinant Adeno-Associated Virus Vectors. Diabetes 50: 515-20, 2001.
  72. *Bingley, P.J.; Bonifacio, E.; Ziegler, A.G.; Schatz, D.; Atkinson, M.; Eisenbarth, G.: Proposed Guidelines on Screening for Risk of Type 1 Diabetes. Diabetes Care 24: 398, 2001.
  73. * Kapturczak, M.H.; Flotte, T.R.; Atkinson, M.A.: Adeno-Associated Virus (AAV) as a Vehicle for Therapeutic Gene Delivery: Improvements in Vector Design and Viral Production Enhance Potential to Prolong Graft Survival in Pancreatic Islet Cell Transplantation for the Reversal of Type 1 Diabetes. Current Molecular Medicine 1: 245-258, 2001.
  74. *Tisch, R.; Wang, B.; Atkinson, M.A.; Serreze, D.V.; Friedline, R.: A Glutamic Acid Decarboxylase 65-Specific Th2 Cell Clone Immunoregulates Autoimmune Diabetes in Nonobese Diabetic Mice. The Journal of Immunology 166: 6925-6936, 2001.
  75. *Atkinson, M.; Eisenbarth, G.: Type 1 Diabetes: New Perspectives on Disease Pathogenesis and Treatment. The Lancet 358: 221-229, 2001.
  76. *Goudy, K.; Song, S.; Wasserfall, C.; Zhang, Y.C.; Kapturczak, M.; Muir, A.; Powers, M.; Scott-Jorgensen, M.; Campbell-Thompson, M.; Crawford, J.M.; Ellis, T.M.; Flotte, T.R.; Atkinson, M.A.: Adeno-Associated Virus Vector Mediated Interleukin-10 Gene Delivery Prevents Type 1 Diabetes in NOD Mice. Proceedings of The National Academy of Sciences , USA . 98: 13913-13918, 2001.
  77. *Peakman, M.; Tree, T.I.; Endl, J.; Endert, P.V.; Atkinson, M.A.; Roep, B.O.: Characterization of Preparations of Glutamic Acid Decarboxylase-65, Proinsulin and the Islet Tyrosine Phosphatase IA-2 for Use in Detection of Autoreactive T Cells in Type 1 Diabetes Mellitus. Report of Phase II of the Second International Immunology of Diabetes Society Workshop for Standardization of T cell Assays in Type 1 Diabetes Mellitus. Diabetes 50: 1749-54, 2001.
  78. *Bonifacio, E.; Atkinson, M.A.; Eisenbarth, G.S.; Kay, T.W.H.; Serreze, D.V.; Chan, E.L.; Singh, B.L.: International Workshop on Lessons from Animal Models for Human Type 1 Diabetes: Identification of Insulin but not Glutamic Acid Decarboxylase or IA-2 as Specific Autoantigens of Humoral Autoimmunity in Nonobese Diabetic Mice. Diabetes 50: 2451-2458, 2001.
  79. *Brod, S.A.; Orlander, P.R.; Lavia, V.R.; Brosnan, P.G.; Hardin, D.S.; Hanninger, E.; Atkinson, M.A., Riley, W.J.: Ingested IFN-alpha prolongs the “Honeymoon” Period in Newly-Diagnosed Type 1 Diabetes Mellitus. Journal of Interferon and Cytokine Research 21:1021-1031, 2001.
  80. *Kapturczak, M.; Zolotukhin, S.; Cross, J.: Powers, M.; Jehle, K.: Inverardi, L.; Pileggi, A.; Flotte, .R.; Nick, H.; Atkinson, M.; Agarwal, A.: Transduction of Human and Murine Pancreatic Islet Cells Using a Bicistronic Recombinant Adeno-Associated Viral Vector. Molecular Therapy 5: 154-160, 2002.
  81. Bonifacio, E.; Atkinson, M.; Eisenbarth, G.; Serreze, D.; Kay, T.W.H.; Lee-Chan, E.; Singh, B.: International Workshop on Lessons from Animal Models for Human Type 1 Diabetes: Analyzing Target Autoantigens of Humoral Immunity in Non-Obese Diabetic Mice. Annals New York Academy of Sciences 958: 1-2, 2002.
  82. *Bowman, M.; Atkinson, M.: Heat Shock Protein Therapy Fails to Prevent Diabetes in NOD Mice. Diabetologia 45: 1350-1351, 2002.
  83. *Zhang, Y.C.; Molano, R.D.; Pileggi, A.; Powers, M.; Wasserfall, C.: Brusko, T.; Flotte, T.; Ellis, T.M.; Ricordi, C.; Atkinson, M.A.; Inverardi, L.: Adeno-Associated Virus Mediated Interleukin-4 Gene Therapy Fails to Enhance Recurrence to Normoglycemia in Syngeneic Marginal Mass Islet Transplants. Transplantation 74: 1184-1186, 2002.
  84. Atkinson, M.A.; Wilson, S.B.: Fatal Attraction: Chemokines and Type 1 Diabetes. Journal of Clinical Investigation 110: 1611-1613, 2002.
  85. *Zhang, Y.C.; Pileggi, A.; Agarwal, A.; Molano, R.D.; Powers, M.; Brusko, T.; Wasserfall, C.; Goudy, K.; Zahr, El; Poggioli, R.; Scott-Jorgensen, M.; Camplbell-Thompson, M.; Crawford, J.M.; Nick, H.; Flotte, T.R.; Elllis, T.M.; Ricordi, C.; Inverardi, L.; Atkinson, M.A.: Adeno-associated virus mediated interleukin-10 gene therapy inhibits autoimmune diabetes recurrence in syngeneic islet transplanted NOD mice. Diabetes 52: 708-716, 2003.
  86. *Chen, S.; Agarwal, A.; Glushakova, O.Y.; Jorgensen, M.S.; Salgar, S.; Croker, B.P.; Madsen, K.M.; Atkinson, M.A.; Hauswirth, W.H.; Berns, K.I.; Tisher, C.C.: Gene Delivery in Renal Tubular Epithelial Cells Using Recombinant Adeno-Associated Viral Vectors. Journal American Society of Nephrology 14: 947-958, 2003.
  87. *Litherland, S.A.; She, J.X.; Schatz, D.; Fuller, K.; Hutson, A.D.; Li., Y.; Grebe, K.M.; Whittaker, D.S.; Bahjat, K.; Hoplins, D.; Fang, Q.; Wasserfall, C.; Cook, R.; Dennis, M.A.; Crokett, S.; Sleasman, J.; Kocher, J.; Muir, A.; Silverstein, J.; Atkinson, M.; Clare-Salzler, M.J.: Aberrant Monocyte Prostaglandin Synthase 2 Expression in Type 1 Diabetes Before and After Disease. Pediatric Diabetes 4: 10-19, 2003.
  88. *Quin, H.Y.; Mahon , J.L.; Atkinson, M.A.; Chaturvedi, P.; Chan, E.L.; Singh, B.: Type 1 diabetes alters anti-hsp90 autoantibody Isotype . Journal of Autoimmunity 20:237-45, 2003.
  89. *Loiler, S.A.; Conlon, T.J.; Song, S.; Warrington, K.H.; Agarwal, A.; Kapturczak, M.; Li, C.; Ricordi, C.; Atkinson, M.A.; Muzyczka, N.; Flotte, T.R.: Targeting Recombinant Adeno-Associated Virus Vectors to Enhance Gene Transfer to Pancreatic Islets and Liver. Gene Therapy 10:1551-58, 2003.
  90. Burkhardt, B.R.; Loiler, S.A.; Anderson, J.A.; Kilberg, M.; Crawford, J.M.; Flotte, T.R.; Goudy, K.S.' Ellis, T.M.; Atkinson, M.A. Glucose-responsive expression of the human insuin promoter in HEP G2 human hepatoma cells. New York Academy of Sciences 1005: 237-241, 2003.
  91. Yu, L.; Eisenbarth, G.; Bonifacio, E.; Thomas, J.; Atkinson, M.; Wasserfall, C.: The Second Murine Autoantibody Workshop: Remarkable Inter-laboratory Concordance for Radiobinding Assays to Identify Insulin Autoantibodies in Non-Obese Diabetic Mice. New York Academy of Sciences 1005: 1-12, 2003.
  92. *K. Goudy, C. Wasserfall, B. Burkhardt, T. Brusko, E. Sobel, S. Song, T. Ellis, T. Flotte, M. Atkinson. Systemic Over Expression of IL-10 Induces CD4+CD25+ Cell Populations In Vivo and Ameliorates Type 1 Diabetes in Nonobese Diabetic Mice in a Dose-Dependent Fashion . Journal of Immunology 171: 2270-2278, 2003.
  93. Atkinson, M.; Gale, E.: Infant Diets and Risk for Type 1 Diabetes: Have We Finally Arrived at an Answer? Journal of the American Medical Association 290:1771-72, 2003.
  94. *Schatz, D.A.; Gale, E.; Atkinson, M.A.: Why can't we prevent type 1 diabetes? Maybe its time to try a different combination. Diabetes Care 26:3326-3328, 2003.
  95. *Song, S.; Goudy, K.; Campbell-Thompson, M.; Wasserfall, C.; Scott-Jorgensen, M.; Wang, J.; Tang, Q.; Ellis, T.; Crawford, J.M.; Atkinson, M.A.; Flotte, T.R.: Recombinant AAV2 Mediated Alpha-1 Antitrypsin Gene Therapy Prevents Type 1 Diabetes in NOD Mice. Gene Therapy 11:181-187, 2004.
  96. *Zhang, Y.C.; Powers, M.; Wasserfall, C.; Brusko, T.; Sihong Song, S.; Flotte, T.R.; Snyder, R.; Potter, M.; Scott-Jorgensen, M.; Campbell-Thompson, M.; Crawford, J.M.; Ellis, T.M.; Atkinson, M.A.: Immunity to Adeno-Associated Virus Delivered Transgenes Imparted by Genetic Predisposition to Autoimmunity. Gene Therapy 11:233-240, 2004.