Post-Transcriptional Regulatory Mechanisms (PTRM)

Journal Club Speaker Schedule
Tuesday @ 10:30 a.m.
Spring 2008    
Date
Speaker
 Paper
01/15/08 Shane Kelly Signal Sequence Coding Region Promotes Nuclear Export of mRNA - PLoS Biol. 5: e322 (Dec 2007)
Supplementary Information
01/22/08 Wei-Jye Lin Switching from Repression to Activation: MicroRNAs Can Up-Regulate Translation - Science 318: 1931 (2007)
01/29/08 Cancelled  
02/05/08 Dori Landry The mechanism of an exceptional case of reinitiation after translation - Genes & Dev. 21: 3149-62 (2007)
02/12/08 Sushmit Maitra Transcript-Specific Decapping and Regulated Stability by Human Dcp2 - Mol. Cell. Biol. 28: 939-48 (2008)
02/19/08 Dan Wang Interactions between UPF1, eRFs, PABP and the exon junction complex - EMBO J. 1-12 (2008)
02/26/08 Alison Dean Cell stress modulates the function of splicing regulatory protein RBM4 - PNAS 104: 2235-40 (2007)
03/04/08 Altaira Dearborn Structural Basis of Dcp2 Recognition and Activation by Dcp1 - Mol. Cell 29: 337-49 (Feb 2008)
03/11/08 Shane Kelly Proteasomal degradation of human release factor eRF3a - RNA 14: 240-5 (2008)
03/18/08 Dori Landry The eIF4G homolog DAP5/p97 supports the translation of select mRNAs - Nuc. Acids Res. 36: 168-78 (2008)
03/25/08 Wei-Jye Lin Stress-dependent relocalization of translationally primed mRNPs - JCB 179: 65-74 (Oct 2007)
04/01/08 Altaira Dearborn Human TOB, an Antiproliferative Transcription Factor, Is a Poly(A)-Binding - Mol. Cell. Biol. 27: 7791-801 (2007)
04/08/08 Dan Wang Degradation of histone mRNA requires oligouridylation followed by decapping - Genes & Dev. 22: 50-65 (2008)
Supplementary Information
04/15/08 Alison Dean rRNA Modifications in an Intersubunit Bridge of the Ribosome - Mol. Cell 28: 965-77 (Dec 2007)
     
Fall 2008    
Date Speaker Paper
08/26/08 Marla Hertz HCV and CSFV IRES domain II mediate elF2 release during 80S ribosome assembly - EMBO J. 26: 795-805 (07)
09/02/08 Sara Conard Puf1p acts in combination with other yeast Puf proteins to control mRNA stability - RNA: 14: 246-62. 
09/09/08 Dan Wang The mRNA Export Factor Gle1 and Inositol Hexakisphosphate Regulate Distinct Stages - Cell 134: 624-33.
09/16/08 Marla Hertz Genetic identification of yeast 18S rRNA residues required... - Genes & Dev. 22: 2242-55 (2008)
09/23/08 Wei-Jye Lin p53 mRNA controls p53 activity by managing Mdm2 functions - Nat. Cell Biol. 10: 1098-1105 (2008)
09/30/08 Shane Kelly Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions... Science 320: 1643 (2008)
10/07/08 Alison Dean Translation initiation by the c-myc mRNA internal ribosome entry sequence... RNA 14: 1579-89 (2008)
10/14/08   No Meeting
10/21/08 Dan Wang eIF3a cooperates with sequences 5' of uORF1 to promote resumption of scanning...Genes & Dev. 22: 2414-25.
10/28/08 Shane Kelly Mature ribosomes are selectively degraded upon starvation by an autophagy...Nature Cell Biol. 10: 602-10 (2008).
11/04/08 Charu Shukla Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association... RNA 14: 1950-58 (2008)
11/11/08 Sara Conard The DEAD-Box RNA Helicase Ded1p Affects and Accumulates in... Mol. Cell. Biol. 19: 984-93 (2008).
11/18/08 Wei-Jye Lin Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops Cell 32: 383-93 (2008).
11/25/08 Charu Shukla Widespread Impact of Nonsense-Mediated mRNA Decay on the Yeast Intronome. Mol. Cell 31: 360-70 (2008).
12/02/08 Alison Dean Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency. Nature (Epub 2008).
     
Possible Topics: mRNA maturation
mRNA export from the nucleus
mRNA turnover
AU Rich elements (AREs)
Translational regulation
Regulated protein turnover
ER stress (regulated protein folding)
Genetic recoding (frame shifting, RNA editing, etc.)
Ribosome function
  IRES function
 
Click here for previous schedule
Revised last: Tuesday, December 2, 2008