MIC 789-00 Journal Club in Biological Crystallography – Dr. Mark Walter

The BCJC revolves around a weekly literature review that focuses on papers that use single crystal X-ray diffraction techniques to solve important questions in structural biology. The participants are encouraged to focus on the methods that allow the problems to be solved. These areas include novel methods of protein expression and purification, crystallization, X-ray data collection, phasing, refinement, and structure analysis methods. Critiques are made on the quality of the structures presented and how structural information is best presented in scientific journals. Emphasis is also placed on novel techniques that synergize with crystallographic techniques leading to new insights into protein structure and function. As needed, the journal club will focus on historically important papers in methods development of protein crystallography.