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Virus Structure and Assembly:
You have reached the Prevelige laboratory in the Department of Microbiology at the University of Alabama at Birmingham. The lab studies virus assembly using a wide variety of techniques.
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Experimental Systems and Approaches:
The lab studies the assembly of two different viruses, the Salmonella typhimurium bacteriophage P22 and HIV. The P22 system affords the advantages of being a well defined system in which genetic manipulations are straightforward.
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Mass Spectrometry of Macromolecular Complexes:
Mass spectrometry has become a powerful technique in structural biology as witnessed by the 2002 Nobel prize in Chemistry.
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